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Dry cow treatment may have an impact on antimicrobial resistance of fecal Escherichia coli

Eight farms practicing selective dry cow treatment were studied. Fecal and quarter milk samples were taken twice at two week intervals within four weeks of dry off and four weeks post calving from 162 cows (84 receiving DCT and 78 receiving no DCT). DCT were either cephapirin or novobiocin. Four E. coli colony forming units were isolated from each fecal sample and MIC for were performed. Difference in MIC from pre-dry to post-calving was assessed. Dry cow treatment was associated with a greater odds of an increase in resistance to ceftiofur although further research is necessary to confirm these findings.


Poirer, et al. 2008. The effect of dry cow treatment on antibiotic resistance of fecal Escherichia coli and of mammary quarter isolates. Proc. NMC Annual Meeting, New Orleans.