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Daily News

15.02.10

Antimicrobial susceptibility of coagulase-negative Staphylococcus isolated from bovine milk

CNS associated with bovine mastitis consist of more than 30 species and subspecies which may have varying levels of resistance to antimicrobials. It has been hypothesized that CNS may serve as a reservoir for the transfer of antimicrobial resistance genes to Staphylococcus aureus. 168 CNS isolates were randomly selected from a collection obtained from three dairy herds and MIC determinations for antimicrobials commonly used for the treatment of bovine mastitis were made for each isolate. Most CNS were susceptible to commonly used antimicrobials; however, S. epidermidis isolates exhibited varying degrees of resistance to erythromycin and pirlimycin. Ampicillin resistance, primarily due to constitutive β-lactamase production, was observed in 29 CNS isolates. Twelve S. epidermidis isolates were resistant to oxacillin (coded for by mecA in 11 isolates) and considered to be multi-drug resistant. These isolates were from the same farm but different cows, suggesting a clonal dissemination. Studying CNS at the species level can yield important information for effective mastitis therapy and management.

Ressources

Sawant, A.A., et al. 2009. Antimicrobial susceptibility of coagulase-negative Staphylococcus isolated from bovine milk. Vet. Microbiol. 134 (1-2):73-81